Related Products of 5334-40-7, These common heterocyclic compound, 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Step 1:4-nitropyrazol-3-carbonyl chloride 4-nitro-pyrazol-3-formic acid (3g, 19.1 mmol), thionyl chloride (100mL) and N, N-dimethylformamide (0.1mL) were added to a 250mL reaction flask. The reaction mixture was heated up to reflux and stirred for 3 hours. After completion of the reaction, the reaction solution was concentrated to obtain the title compound (3.33g), the crude product was used directly for the subsequent reaction. (MS: [M+1] none)
Statistics shows that 4-Nitro-1H-pyrazole-3-carboxylic acid is playing an increasingly important role. we look forward to future research findings about 5334-40-7.