Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3112-31-0, name is 1H-Pyrazole-3,5-dicarboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., category: pyrazoles-derivatives
A solution of the pyrazole 3,5-dicarboxylicacid (1.60 mmol, 0.25 g) in thionyl chloride (4 mL) was heated underreflux for 2 h. Excess solvent was then distilled off and the crude 23dried under vacuum. A solution of the crude pyrazole diacylchloride 23,triethylamine (4.8 mmol, 0.67 mL) and DMAP (0.32 mmol, 0.039 g) inanhydrous dichloromethane (13 mL) was cooled in an ice bath and theamine 24 (3.28 mmol, 0.782 g) was added slowly as a solution indichloromethane (3 mL). The reaction mixture was allowed to gradually warm up to room temperatureand stirred overnight. The mixture was then washed with 10percent hydrochloric acid and water, and theorganic layer separated. The aqueous layer was further extracted two more times with dichloromethane.Combined organics were dried with anhydrous sodium sulfate, filtered, concentrated and purified by flashcolumn chromatography to furnish the title compound a white solid in 85percent yield.
According to the analysis of related databases, 3112-31-0, the application of this compound in the production field has become more and more popular.