Adding a certain compound to certain chemical reactions, such as: 930-36-9, name is 1-Methylpyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 930-36-9, HPLC of Formula: C4H6N2
Step 1 : 4-iodo- l -methyl- lH-pyrazole A mixture of 1 -methy 1-1 H-pyrazole (7) (37 gm, 0.6090 moles), iodine (57. 1 gm, 0.225 moles), hydrogen peroxide (9.2 gm, 0.27 moles) and DI water ( 1 10 ml) were stirred for 24 hour at 20-30C. Progress of the reaction was monitored by HPLC and TLC. The reaction mixture was cooled to 5- 10C. The reaction mixture was quenched with 20% aqueous sodium bisulfite ( 100 ml) and stirred for 1 hour at 5-10C. The solid product obtained was filtered off, washed with cold DI water ( 100 ml) and dried at 40-45C to yield the product, 4-iodo- l – methyl- 1 H-pyrazole. Dry wt : 56 gm Yield : 1.51 w/w (60%)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methylpyrazole, other downstream synthetic routes, hurry up and to see.