Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 30169-25-6, name is 3,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine, A new synthetic method of this compound is introduced below., Quality Control of 3,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine
Benzimidazole (248 mg, 2.1 mmol) was added to tetrazine 1a (270 mg, 1 mmol) in acetonitrile (5 mL), the mixture was stirred for 3 h with heating to 75 C. Then, after hot filtration, the substance was washed with hot acetonitrile on the filter. The yield was 299 mg (95%). A red powder, m.p. 332-334 C. Found (%): C, 60.74; H, 3.41; N, 35.42. C16H10N8. Calculated (%): C, 61.14; H, 3.21; N, 35.65. 1H NMR (DMSO-d6), delta: 7.48-7.55, 7.56-7.62, 7.91-7.97, 8.45-8.52 (both m, 2 H each, H(4), H(5), H(6), H(7) in benzimidazolyls); 9.43 (both s, 2 H each, H(2) in benzimidazolyls). 13C NMR (DMSO-d6), delta: it was technically impossible to register 13C NMR spectrum because of the poor solubility of compound 1d.
The synthetic route of 30169-25-6 has been constantly updated, and we look forward to future research findings.