Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 81945-73-5, name is 1H-Pyrazol-1-ol, This compound has unique chemical properties. The synthetic route is as follows., name: 1H-Pyrazol-1-ol
1. N-2-[4-(1,1-Dimethylethoxy)phenoxy]ethoxypyrazole A solution of 12.7 g (0.15 mol) of N-hydroxypyrazole in 20 ml of DMF was added dropwise to a suspension of 4.95 g (1.1 eq.) of NaH (80% dispersion in mineral oil) in 40 ml of DMF at RT, and the mixture was heated at 70 C. for 1 h. A solution of 40.95 g (0.15 mol) of 2-[4-(1,1-dimethylethoxy)phenoxy]ethyl bromide in 100 ml of DMF was added and the mixture was then heated at 125 C. for 15 h. The solvent was then stripped off in a rotary evaporator, the residue was taken up in ethyl acetate, and the solution was washed twice each with 5% strength NaOH solution and water. Drying and removal of the solvent under reduced pressured resulted in 38.4 g (93%) of the required compound as a pale oil which was employed without further purification in the next stage. 1 H-NMR (250 MHz, CDCl3): delta=7.38 (d, 1H); 7.28 (d, 1H); 6.93 (d, 2H); 6.83 (d, 2H); 6.17 (t, 1H); 4.63 (m, 2H); 4.17 (m, 2H); 1.30 (s, 9H) ppm
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 81945-73-5.