Adding a certain compound to certain chemical reactions, such as: 25016-12-0, name is 1,3-Dimethyl-1H-pyrazole-4-carbaldehyde, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 25016-12-0, Quality Control of 1,3-Dimethyl-1H-pyrazole-4-carbaldehyde
(4) 6.3 g of 1,3-dimethyl-1H-pyrazole-4-carbaldehyde (0.052 mol) and2.9 g of ethyl isocyanate (0.026 mol)Add 30mL of water,And heated to 40 C in the air and stirred for 3 hours;After the reaction, add 50% sodium hydroxide aqueous solution to the reaction mixture and mix well.It was then extracted with dichloromethane to remove impurities;The aqueous phase was adjusted to pH = 2-3, filtered, the filter cake was washed, and the solid was collected.4.9 g of 1,3-dimethyl-1H-pyrazole-4-carboxylic acid was obtained; the purity was 99% and the yield was 79%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,3-Dimethyl-1H-pyrazole-4-carbaldehyde, and friends who are interested can also refer to it.