Adding a certain compound to certain chemical reactions, such as: 2075-46-9, name is 4-Nitro-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2075-46-9, Computed Properties of C3H3N3O2
Bromoethanol (1.9 g, 15.57 mmol) and potassium carbonate (2.9 g, 21.12 mmol) were sequentially added to a solution of 4-nitropyrazole (1.6 g, 14.16 mmol) in acetonitrile (20 mL). The suspension was stirred at 60 C. for 16 hours. After cooling to room temperature, the mixture was filtered and the filter cake was washed with acetonitrile (10 mL). The filtrate was concentrated under reduced pressure to give 20-c as a yellow oil (1.1 g, yield 49.5%), which was directly used for the next step without purification.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Nitro-1H-pyrazole, and friends who are interested can also refer to it.