Reference of 154471-65-5,Some common heterocyclic compound, 154471-65-5, name is 1-Methyl-3-(trifluoromethyl)-1H-pyrazole, molecular formula is C5H5F3N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
To a stirred solution of 3.8 g (25.3 mmol) l-methyl-3-(trifluoromethyl)- lH-pyrazole (2) in dichloromethane (75 ml) was added 3.42 ml (26 mmol) of ethyltriflate. After heating the mixture to reflux for 6 hours the low boiling components were removed under reduced pressure to yield 2.4 g (29 %) of the ionic liquid 5 as amber coloured oil
The synthetic route of 154471-65-5 has been constantly updated, and we look forward to future research findings.