Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C4H3N3O4
In a 250 mL round bottom flask, 7.5 g (36.6 mmol) of crude I-b’ was added. 4-nitro-1H-pyrazole-3-carboxylic acid 6.3 g (40.1 mmol), EDC¡¤HCl 8.4 g (44.0 mmol), HOBt 6.0g (44.4mmol) and anhydrous DMF 100mL, Stir at room temperature for 24 h. The disappearance of the starting material by TLC (methanol: chloroform = 1:10). The reaction solution was poured into 200 mL of ice water. A large amount of pale yellow solid is precipitated, Rest, Thinking about a yellow solid, The obtained crude product was recrystallized from ethyl acetate and methanol to give (I-e) 11.1 g. The yield was 88.2%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 5334-40-7.