Synthetic Route of 72760-85-1, These common heterocyclic compound, 72760-85-1, name is 3-Amino-5-(methylthio)-1H-pyrazole-4-carbonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of amino-1H-pyrazole (1 mmol), aldehyde (2 mmol), TMSCN (1.2 mmol) in [Bmim]BF4 (0.5 g) was heated at 120 C for 24 h. After cooling, the reaction mixture was washed with water (5 mL) and the residue washed with MeOH to afford pure product.
The synthetic route of 72760-85-1 has been constantly updated, and we look forward to future research findings.