Related Products of 56426-35-8, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 56426-35-8 name is Methyl 5-phenyl-1H-pyrazole-3-carboxylate, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Intermediate 96 (320mg, 1.S8mmol) was dissolved in THF/water (l5mL, 1:1), lithiumhydroxide monohydrate (146mg, 3.48mmol) was added and the reaction mixture wasstirred for 2h. The THF was removed in vacuo and the aqueous solution was acidified to pH 1 with 1M aq HC1. The precipitate was collected by filtration to give the title0 . + +compound (232mg, 78/o) as a yellow solid. LCMS: ES 189.0 [IVIH]
At the same time, in my other blogs, there are other synthetic methods of this type of compound, Methyl 5-phenyl-1H-pyrazole-3-carboxylate, and friends who are interested can also refer to it.