143426-52-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 143426-52-2 name is 1-(4-(Chloromethyl)phenyl)-1H-pyrazole, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
4 mmol of the compound IIIb was dissolved in 20 mL of acetonitrile, and intermediate 77 mmol and 8 mmol ofcesium carbonatewere added thereto at room temperature.After heating, the reaction was refluxed for 13 hours.The reaction was stopped, the reaction solution was rotary evaporated to dryness under reduced pressure, the resulting residue was purified by columnseparation and purification to give the title compound analysis Ib
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(4-(Chloromethyl)phenyl)-1H-pyrazole, and friends who are interested can also refer to it.