A simple and environmentally benign nitration of pyrazoles by impregnated bismuth nitrate was written by Ravi, P.;Gore, Girish M.;Tewari, Surya P.;Sikder, Arun K.. And the article was included in Journal of Heterocyclic Chemistry in 2013.HPLC of Formula: 54210-32-1 This article mentions the following:
A facile, rapid, and environmentally friendly synthesis of nitropyrazoles in good yields was reported using silica-bismuth nitrate and silica-sulfuric acid-bismuth nitrate at room temperature The relatively non-toxic nature, ease of handling, easy availability, and low cost make the present procedure attractive for the nitration of a wide variety of diazoles in drug and pharmaceutical industries. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1HPLC of Formula: 54210-32-1).
1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. HPLC of Formula: 54210-32-1
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics