Nitro azines. 20. Simple syntheses of pyrazolo-condensed nitropyridines from aliphatic nitro synthons and aminopyrazoles was written by Rusinov, V. L.;Petrova, A. Yu.;Chupakhin, O. N.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1992.Recommanded Product: 55361-49-4 This article mentions the following:
Treating aminopyrazoles I (R, R1 = H, Me, Ph) with the Na salt of O2NCH(CHO)2 in water gave 65-75% pyrazolopyridines II (R = H, R1 = Ph, Me, H; R = Me, R1 = Me, H; R = Ph, R1 = H); and in AcOH 70-90% II (R = H, Me, Ph, R1 = Ph; R = H, Me, R1 = Me) were obtained. Addnl. obtained were pyrazolopyridines III (R = H, Me, R1 = Ph). In the experiment, the researchers used many compounds, for example, 1-Ethyl-1H-pyrazol-3-amine (cas: 55361-49-4Recommanded Product: 55361-49-4).
1-Ethyl-1H-pyrazol-3-amine (cas: 55361-49-4) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 鎺矯).Pyrazole used as a ligand to prepare organometallic compounds. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.Recommanded Product: 55361-49-4
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics