Liu, Yuting et al. published their research in Research on Chemical Intermediates in 2015 | CAS: 5334-39-4

3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Electric Literature of C4H5N3O2

Synthesis, characterization, and antimicrobial activity of novel heterocyclic compounds containing a ferrocene unit via Michael addition reaction was written by Liu, Yuting;Zhang, Hanli;Yin, Dawei;Chen, Dan. And the article was included in Research on Chemical Intermediates in 2015.Electric Literature of C4H5N3O2 This article mentions the following:

A series of novel heterocyclic compounds containing a ferrocene unit were synthesized by reacting ferrocenylchalcone with pyrazolyl amine or triazolyl amine via Michael addition reaction. A novel synthetic route of ferrocenylchalcones was developed in which cinnamic acid and ferrocene were used as starting materials and phosphorus pentachloride was used as acylating agent. The structure of these newly synthesized compounds was confirmed by IR, elemental anal., 1H NMR, and 13C NMR. The antibacterial activity and min. inhibitory concentration (MIC) of all compounds were screened for Escherichia coli, Saccharomyces aureus, Streptococcus, Actinomycete, and Saccharomyces cerevisiae in vitro by filter paper disk diffusion method, and agar dilution method, resp. The compounds exhibited moderate to excellent antibacterial activity in comparison to Ampicillin used as reference drug and MIC values between 1 and 64 娓璯/mL. Among these tested compounds, I (R= H, Me) show the best inhibitory activity. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4Electric Literature of C4H5N3O2).

3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Electric Literature of C4H5N3O2

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics