Nikiforov, Alexey A. et al. published their research in Polyhedron in 2021 | CAS: 19959-77-4

2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Application In Synthesis of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine

Penta- and dinuclear carboxylate nickel(II) complexes with pyrazole-based ligands: Syntheses, magnetic properties and DFT calculations was written by Nikiforov, Alexey A.;Dubrov, Evgenii N.;Blinou, Daniil O.;Gurzhiy, Vladislav V.;Selyutin, Artem A.;Klyukin, Ilya N.;Zhdanov, Andrey P.;Minkovich, Alexander E.;Panina, Natalia S.;Eremin, Alexei V.. And the article was included in Polyhedron in 2021.Application In Synthesis of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine This article mentions the following:

<<One pot>> reactions of pyrazole-based ligands Hdmpz and PyPz with in situ formed carboxylate precursors led to the formation of mono- and di-aqua-bridged binuclear compounds, as well as pentanuclear hydroxo-bridged compound: [Ni2(μ-OH2)(μ-O2CC(CH3)3)2(O2CC(CH3)3)2(PyPz)2] (1), [Ni5(μ3-OH)2(μ-O2CPh)8(PyPz)4].4.73MeCN (2), [Ni2(μ-OH2)(μ-O2CPh)2(O2CPh)2(Hdmpz)4] (3), [Ni2(μ-OH2)2(μ-O2CPh)(O2CPh)2(Hdmpz)4](O2CPh)•2.5H2O (4) (Hdmpz = 3,5-dimethylpyrazole, PyPz = 2-(5-Methyl-1H-pyrazol-3-yl)pyridine). Compounds were characterized by structural and spectral methods, thermogravimetric anal. and magnetic measurements were also performed. It was noted, that structural motif of forming compounds are determined by the structure of carboxylate precursors formed in situ and properties of N-ligands. Comparison of magnetic measurements data, structural data, and DFT calculations allows us to conclude that in the case of investigated compounds the equilibrium between spin isomers with different multiplicities, close energy values and close geometrical structure (no data) can be realized. In the experiment, the researchers used many compounds, for example, 2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4Application In Synthesis of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine).

2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Application In Synthesis of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics