Synthesis of 1H-pyrazolo[3,4-b]pyridine steroids was written by Haeufel, Jochen;Pech, Hans;Breitmaier, Eberhard. And the article was included in Chemiker-Zeitung in 1973.HPLC of Formula: 3528-58-3 This article mentions the following:
Androstenopyrazolopyridines I, II (R = H, Me; R1 = Me, Et, Ph) (8 compounds) were prepared in 38-75% yields by condensing aminopyrazoles III with 2-(hydroxymethylene)testosterone or 16-(hydroxymethylene)epiandrosterone. In the experiment, the researchers used many compounds, for example, 1-Ethyl-1H-pyrazol-5-amine (cas: 3528-58-3HPLC of Formula: 3528-58-3).
1-Ethyl-1H-pyrazol-5-amine (cas: 3528-58-3) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazoles and pyrimidines have diverse biological and pharmacological activities. There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. Pyrazofurin is important antimicrobial drug and 2-methylpyrimidine-4-ylamine derivatives I and II were found to be effective inhibitors of Escherichia coli PDHc-E1 with antibacterial and antifungal activity.HPLC of Formula: 3528-58-3
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics