Inhibitory effects of pyrazoles on soil nitrification: effects of chemical structure was written by Shi, Yunfeng;Zhang, Lili;Wu, Zhijie. And the article was included in Fresenius Environmental Bulletin in 2012.COA of Formula: C5H7ClN2 This article mentions the following:
Pyrazoles are nitrification inhibitors with good inhibitory effects. In this study, chem. structure of pyrazoles and its relationship with nitrification inhibitory effects were studied through aerobic incubation, and the optimal concentrations of three nitrification inhibitors with better nitrification inhibitory effects were explored, including 3,4-dimethylpyrazole phosphate (DMPP), 1-carboxamide-3-methylpyrazole (CMP), and 4-chloro-3-methylpyrazole (ClMP). The results showed that all the pyrazoles could effectively inhibit NH4+ oxidation in soils. Specifically, inhibitory effects of 3-methylpyrazole, 3,4-dimethylpyrazole, 4-chloro-3-methylpyrazole and their derivatives were the best. When the 4-position was substituted by chlorine atoms, nitrification inhibitory effects of pyrazoles could be significantly improved, which were not affected by the substitution at 1-position (hydroxymethylation and amidation) and neutralization. Nitrification inhibitory rate and inhibitory duration were increased with increasing consumptions of nitrification inhibitor pyrazoles. The optimal concentrations of three nitrification inhibitors with better nitrification inhibitory effects, including DMPP, CMP and ClMP, should be controlled in the range of 0.25-1.0% of N application, and the nitrification duration was about 56 days. In the experiment, the researchers used many compounds, for example, 4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8COA of Formula: C5H7ClN2).
4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.COA of Formula: C5H7ClN2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics