75415-03-1, A common compound: 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine, belongs to pyrazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
General procedure: Compound 4a (2 mmol), NaH (2.4 mmol) and indole were dissolved in DMF (10 mL). The reaction mixture was stirred at room temperature for 12h before diluted with water (20 mL) and extracted with ethyl acetate (30 mL ¡Á 3). The organic layer was concentrated in vacuum. Purication by ash column chromatography gave the target product 5h.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(1H-Pyrazol-3-yl)pyridine, other downstream synthetic routes, hurry up and to see.