Transition metal complexes with pyrazole-based ligands Part 12. Characterisation and thermal decomposition of CuCl2 complexes with di- and trisubstituted pyrazoles was written by Szecsenyi, K. Meszaros;Leovac, V. M.;Jacimovic, Z. K.;Cesljevic, V. I.;Kovacs, A.;Pokol, G.. And the article was included in Journal of Thermal Analysis and Calorimetry in 2001.COA of Formula: C6H9N3O This article mentions the following:
The synthesis of copper(II) chloride complexes with 3,5-dimethylpyrazole, 1-carboxamide-3,5-dimethylpyrazole, 5-amino-4-carboxamide-1-phenylpyrazole and 4-acetyl-3-amino-5-methylpyrazole is described. The compounds were characterized by elemental anal., FTIR spectroscopy, thermal methods, magnetic moment and molar conductivity measurements. Elimination of the carboxamide group from the 1-carboxamide-3,5-dimethylpyrazole takes place to give 3,5-dimethylpyrazole complexes. Thermal decomposition of the dichloro(3,5-dimethylpyrazole)copper(II) complex results in an unstable intermediate with a stoichiometric composition The decomposition of the other compounds is continuous. In the experiment, the researchers used many compounds, for example, 3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5COA of Formula: C6H9N3O).
3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.COA of Formula: C6H9N3O
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics