Studies on some new bridgehead nitrogen heterocyclic cyanine dyes was written by Koraiem, A. I. M.;Shindy, H. A.;Abu El-Hamd, R. M.. And the article was included in Proceedings – Indian Academy of Sciences, Chemical Sciences in 1999.Safety of 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one This article mentions the following:
New asym. mono-(tri)-methine and azomethine cyanine dyes of pyrazolo[5,4-b]quinolino[a,b]-1,4-pyra-(oxa)-zinium bromide salts were prepared The newly synthesized cyanines were identified by elemental and spectral analyses. The visible absorption spectra of some selected dyes were investigated in single and mixed solvents, and also in aqueous buffer solutions The spectral shifts were studied in relation to mol. structure and in terms of medium effects. Mol. complex formation with DMF was verified through mixed-solvent studies. In the experiment, the researchers used many compounds, for example, 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9Safety of 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one).
4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Safety of 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics