Metal-catalyzed oxidations. Part 6. Molybdenum-catalyzed olefin epoxidation: ligand effects was written by Thiel, Werner R.;Eppinger, Joerg. And the article was included in Chemistry – A European Journal in 1997.Name: 2-(5-Methyl-1H-pyrazol-3-yl)pyridine This article mentions the following:
0E synthesized substituted pyrazolylpyridine ligands to examine their donor properties by spectroscopic (IR, NMR) and computational (AM1) methods. The influence of the substitution patterns on spectroscopic and thermodn. features of molybdenum oxobisperoxo complexes [(L-L)MoO(O2)2] [L-L = 2-(1-alkyl-3-pyrazolyl)pyridine/pyrazine] correlates with the activities of the complexes in catalytic olefin epoxidation reactions. This further proof for the relation between the Lewis acidity and the catalytic activity of epoxidation catalysts supports a reaction mechanism in which the peroxo complex activates the oxidizing agent (H2O2, ROOH) instead of directly transferring an oxygen atom from a η2-peroxo ligand to the olefin. In the experiment, the researchers used many compounds, for example, 2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4Name: 2-(5-Methyl-1H-pyrazol-3-yl)pyridine).
2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Name: 2-(5-Methyl-1H-pyrazol-3-yl)pyridine
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics