Mi, Pengbing et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2019 | CAS: 73387-46-9

3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. Protonation of pyrazole in strong acid leads to pyrazolium cations, which undergo electrophilic substitution preferentially at C3 rather than C4. The pyrazole anion is not reactive toward nucleophiles but is mostly reactive to electrophiles.Safety of 3-(4-Bromophenyl)-1H-pyrazole

Molybdenum-silver co-catalyzed cycloaddition of alkynes with N-isocyanoiminotriphenylphosphorane (NIITP): An efficient strategy for the synthesis of monosubstituted pyrazoles was written by Mi, Pengbing;Lang, Jiajia;Lin, Shaojian. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Safety of 3-(4-Bromophenyl)-1H-pyrazole This article mentions the following:

A new molybdenum-silver co-catalyzed [3+2]-cycloaddition of alkynes RCCH (R = 4-FC6H4, cyclopentyl, pyridin-2-yl, etc.) with N-isocyanoiminotriphenylphosphorane (NIITP) is described. The NIITP serves as a non-toxic, facile “CN-N” source. Over 30 substrates were successfully converted to the desired pyrazole compounds I in good to excellent yields. In the experiment, the researchers used many compounds, for example, 3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9Safety of 3-(4-Bromophenyl)-1H-pyrazole).

3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. Protonation of pyrazole in strong acid leads to pyrazolium cations, which undergo electrophilic substitution preferentially at C3 rather than C4. The pyrazole anion is not reactive toward nucleophiles but is mostly reactive to electrophiles.Safety of 3-(4-Bromophenyl)-1H-pyrazole

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics