Shekarrao, Kommuri et al. published their research in RSC Advances in 2014 | CAS: 3528-58-3

1-Ethyl-1H-pyrazol-5-amine (cas: 3528-58-3) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor–donor motifs, whether as a monocyclic ring or as a fused indazole ring. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Application In Synthesis of 1-Ethyl-1H-pyrazol-5-amine

Microwave-assisted palladium mediated efficient synthesis of pyrazolo[3,4-b]pyridines, pyrazolo[3,4-b]quinolines, pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a]quinazolines was written by Shekarrao, Kommuri;Kaishap, Partha Pratim;Saddanapu, Venkateshwarlu;Addlagatta, Anthony;Gogoi, Sanjib;Boruah, Romesh C.. And the article was included in RSC Advances in 2014.Application In Synthesis of 1-Ethyl-1H-pyrazol-5-amine This article mentions the following:

An efficient method for the synthesis of pyrazole-fused heterocycles via the palladium-catalyzed solvent-free reaction of β-halovinyl or o-haloaryl aldehydes and 3-aminopyrazoles or 5-aminopyrazoles under microwave irradiation conditions in good yields was developed. This method is applicable for the efficient synthesis of a wide range of substituted pyrazolo[3,4-b]pyridines, e.g., I, pyrazolo[3,4-b]quinolines, e.g., II, pyrazolo[1,5-a]pyrimidines, e.g., III (R1 = H, Me, 4-MeOC6H4; R2 = 4-MeC6H4, 3-thienyl, 2-naphthyl, R3 = H; R2R3 = o-C6H4CH2CH2, etc.) and pyrazolo[1,5-a]quinazolines, e.g., IV. Four of the synthesized pyrazole fused compounds, including I, II, and III (R1 = H; R2 = 4-MeC6H4; R3 = H), showed in vitro cytotoxic activities almost comparable to the drug doxorubicin against the cervical HeLa cancer cell line and prostate DU 205 cancer cell line. In the experiment, the researchers used many compounds, for example, 1-Ethyl-1H-pyrazol-5-amine (cas: 3528-58-3Application In Synthesis of 1-Ethyl-1H-pyrazol-5-amine).

1-Ethyl-1H-pyrazol-5-amine (cas: 3528-58-3) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor–donor motifs, whether as a monocyclic ring or as a fused indazole ring. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Application In Synthesis of 1-Ethyl-1H-pyrazol-5-amine

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics