Optimization of synthesis of nitroimidazoles and nitropyrazoles based on polarographic investigations was written by Dumanovic, D.;Kosanovic, Dj.;Zuman, P.. And the article was included in Heterocycles in 1994.Safety of 1-Methyl-3-nitro-1H-pyrazole This article mentions the following:
A direct, simple, fast, and inexpensive polarog. method enables selective determinations of nitroimidazoles or nitropyrazoles in mixtures, which can be used for monitoring synthetic processes and selecting optimal conditions for synthesis. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1Safety of 1-Methyl-3-nitro-1H-pyrazole).
1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Safety of 1-Methyl-3-nitro-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics