Effects of hydrogen bond on the melting point of azole explosives was written by Wang, Jian-Hua;Shen, Chen;Liu, Yu-Cun;Luo, Jin;Duan, Yingjie. And the article was included in Journal of Molecular Structure in 2018.Safety of 3-Methyl-4-nitro-1H-pyrazole This article mentions the following:
M.p. is an important index to determine whether an explosive can be a melt cast carrier. In this study, the relationship among the mol. structure, crystal structure, and m.p. of explosives was investigated by using nitroazole compounds Hydrogen bonds influence crystal packing modes in chem. understandable ways. Hydrogen bonds also affect the changes in entropy and enthalpy in balancing melting process. Hence, different types of hydrogen bonds in explosive crystal structures were compared when the relationship between the mol. structure and the m.p. of nitroazole explosives were analyzed. The effects of Me and amino groups on intermol. hydrogen bonds were also compared. Results revealed that the Me and amino groups connected on the N(1) of the heterocyclic compound can reduce the m.p. of azole explosive. This finding is possible because Me and amino groups destroy the intermol. hydrogen bond of the heterocyclic compound In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4Safety of 3-Methyl-4-nitro-1H-pyrazole).
3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Safety of 3-Methyl-4-nitro-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics