Reactions of β-aminoenones with acetylhydrazine, semicarbazide and methoxycarbonylhydrazine. Synthesis of 1-acetyl-, 1-carboxamide- or methyl 1-carboxylated pyrazole derivatives was written by Alberola, Angel;Calvo, Luis;Ortega, Alfonso Gonzalez;Sadaba, M. Luisa;Sanudo, M. Carmen;Granda, Santiago Garcia;Rodriguez, Elena Garcia. And the article was included in Heterocycles in 1999.Product Details of 934-48-5 This article mentions the following:
Acetylhydrazine, semicarbazide and methoxycarbonylhydrazine react with β-aminoenones to give regioselectively the corresponding N-acetyl- or N-carboxypyrazole derivatives The reactions are highly regioselective and occur via 5-hydroxypyrazolines, which in several cases can be isolated and characterized. In the experiment, the researchers used many compounds, for example, 3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5Product Details of 934-48-5).
3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Product Details of 934-48-5
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics