Perez, Jose Antonio et al. published their research in Inorganica Chimica Acta in 2005 | CAS: 19959-77-4

2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.Related Products of 19959-77-4

Synthesis and characterisation of palladium(II) and platinum(II) compounds containing pyrazole-derived ligands: crystal structure of [PdCl2(HL1)] (HL1 = 3-phenyl-5-(2-pyridyl)pyrazole) was written by Perez, Jose Antonio;Pons, Josefina;Solans, Xavier;Font-Bardia, Merce;Ros, Josep. And the article was included in Inorganica Chimica Acta in 2005.Related Products of 19959-77-4 This article mentions the following:

Reaction of the ligands 3-phenyl-5-(2-pyridyl)pyrazole (HL1), 3,5-bis(2-pyridyl)pyrazole (HL2), 3-methyl-5-(2-pyridyl)pyrazole (HL3) and 3-methyl-5-phenylpyrazole (HL4) with [MCl2(MeCN)2] (M = Pd(II), Pt(II)) or [PdCl2(cod)] gives [PdCl2(HL)2] (HL = HL1, HL2, HL3), [Pt(L)2] (L = L1, L2, L3) and [MCl2(HL4)2] (M = Pd(II), Pt(II)). The new complexes were characterized by elemental analyses, conductivity measurements, IR and 1H NMR spectroscopies. The crystal and mol. structure of [PdCl2(HL1)] was resolved by x-ray diffraction, and consists of monomeric cis-[PdCl2(HL1)] mols. The Pd center has a typical square planar geometry, with a slight tetrahedral distortion. The tetracoordinated metal atom is bonded to one pyridine N, one pyrazolic N and two chloro ligands in a cis disposition. The ligand HL1 is not completely planar. In the experiment, the researchers used many compounds, for example, 2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4Related Products of 19959-77-4).

2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.Related Products of 19959-77-4

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics