Vinogradov, Vasilii M. et al. published their research in Mendeleev Communications in 1993 | CAS: 5334-39-4

3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.Recommanded Product: 5334-39-4

N-Amination of pyrazoles: a general approach was written by Vinogradov, Vasilii M.;Dalinger, Igor L.;Shevelev, Svyatoslav A.. And the article was included in Mendeleev Communications in 1993.Recommanded Product: 5334-39-4 This article mentions the following:

A general approach to N-amination of pyrazoles, allowing the synthesis of previously inaccessible N-aminopyrazoles with electron-acceptor substituents in the ring, has been proposed, consisting of treatment of the pyrazoles with hydroxylamine-O-sulfonic acid in aqueous media at controlled pH depending on the pKa of the pyrazole. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4Recommanded Product: 5334-39-4).

3-Methyl-4-nitro-1H-pyrazole (cas: 5334-39-4) belongs to pyrazole derivatives. Pyrazole has two ring nitrogen atoms in which N1 is pyrrolic and N2 is pyridine-like. The N1 nitrogen is not reactive but is deprotonated in the presence of a base-forming anion. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.Recommanded Product: 5334-39-4

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics