Thermal rearrangement of v-triazolo[1,5-a]pyridine-3-acraldehydes into 3-methyl-5-(2-pyridyl) pyrazoles was written by Jones, Gurnos;Davies, Leslie Stuart. And the article was included in Journal of the Chemical Society [Section] C: Organic in 1971.Synthetic Route of C9H9N3 This article mentions the following:
The cis-v-triazolo[1,5-a]pyridine-3-acraldehyde (I) was thermally rearranged to 3-methyl-5-(2-pyridyl)pyrazole-4-carboxaldehyde (II) and 3-methyl-5-(2-pyridyl)pyrazole (III). The trans isomer of I gave only III. KMnO4 oxidation of II gave the corresponding acid, which was decarboxylated to III. III was prepared by the reaction of 1-(2-pyridyl)-1,3-butanedione with N2H4. In the experiment, the researchers used many compounds, for example, 2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4Synthetic Route of C9H9N3).
2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.Synthetic Route of C9H9N3
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics