Perevalov, V. P. et al. published their research in Khimiya Geterotsiklicheskikh Soedinenii in 1990 | CAS: 54210-32-1

1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.Related Products of 54210-32-1

Reduction of nitro- and dinitro-1-methylpyrazoles was written by Perevalov, V. P.;Baryshnenkova, L. I.;Manaev, Yu. A.;Bezborodov, B. V.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1990.Related Products of 54210-32-1 This article mentions the following:

Reduction of 1-methyl-3-nitropyrazole by NaHS gives dimethylazoxypyrazole (I) and reduction of 1-methyl-3,5-dinitropyrazole gives a 3:1 mixture of 5-amino-1-methyl-3-nitropyrazole and dimer II. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1Related Products of 54210-32-1).

1-Methyl-3-nitro-1H-pyrazole (cas: 54210-32-1) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. The presence of both electronegative nitrogen atoms in the pyrazole ring reduces the electron density of the C3- and C5-positions leaving electron density of C4-position unaltered. Thus the C4-position is vulnerable to electrophilic attack. The C3 electrophilic-position may undergo deprotonation in the presence of a strong base leading to ring opening.Related Products of 54210-32-1

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics