Assembly of dinuclear copper(II) complexes based on a tridentate pyrazol-pyridine ligand: Crystal structures and magnetic properties was written by Yang, Feng-Lei;Zhu, Guang-Zhou;Liang, Bei-Bei;Shi, Yan-Hui;Li, Xiu-Ling. And the article was included in Polyhedron in 2017.Safety of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine This article mentions the following:
Three dinuclear copper(II) complexes, [Cu2(μ-L)2X2] (X = Cl–, 1; X = NO3–, 2; X = CH3COO–, 3), were synthesized using the relevant Cu2+ salts with the tridentate ligand 2-(5-methyl-1H-pyrazol-3-yl)pyridine (HL) by a diffusion or solvothermal method. These compounds were all characterized by element analyses, IR and x-ray single-crystal diffraction. All the complexes afford a di-ligand-bridged Cu2 unit, in which the two Cu2+ ions and the two ligands are almost coplanar. Each Cu2+ ion is chelated by the (N-N)pyridine-pyrazole pocket and doubly bridged by the (N-N)pyrazole groups, leaving the remaining coordination positions occupied by different anionic coligands to balance the charge. Magnetic investigations reveal that the τ values have more effect than the coplanarity of the Cu-(N:N)2-Cu unit on the antiferromagnetic strength in this system. In the experiment, the researchers used many compounds, for example, 2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4Safety of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine).
2-(5-Methyl-1H-pyrazol-3-yl)pyridine (cas: 19959-77-4) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Safety of 2-(5-Methyl-1H-pyrazol-3-yl)pyridine
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics