O’Callaghan, C. N. et al. published their research in Proceedings of the Royal Irish Academy in 1976 | CAS: 934-48-5

3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide

Reaction of hydrazine hydrate with 4-alkyl-1-cyanoacetylthiosemicarbazides was written by O’Callaghan, C. N.. And the article was included in Proceedings of the Royal Irish Academy, Section B: Biological, Geological and Chemical Science in 1976.Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide This article mentions the following:

NCCH2CONHNHCSNHR (R = Me, Et, Pr, PhCH2) were cyclized by H2NNH2.H2O at 20° to cyanomethyltriazolinethiones I, which at higher temperature were converted to II. In the experiment, the researchers used many compounds, for example, 3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide).

3,5-Dimethyl-1H-pyrazole-1-carboxamide (cas: 934-48-5) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Quality Control of 3,5-Dimethyl-1H-pyrazole-1-carboxamide

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics