Bhat, Mashooq Ahmad et al. published their research in Journal of Chemistry in 2019 | CAS: 73387-46-9

3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. Recommanded Product: 73387-46-9

Enaminone-derived pyrazoles with antimicrobial activity was written by Bhat, Mashooq Ahmad;Al-Omar, Mohamed A.;Naglah, Ahmed M.;Khan, Abdul Arif. And the article was included in Journal of Chemistry in 2019.Recommanded Product: 73387-46-9 This article mentions the following:

A series of pyrazoles I [R = 4-methoxy, 4-bromo, 4-morpholino, etc.; R1 = H, 2-phenylacetyl] derived from the substituted enaminones were synthesized and were evaluated for antimicrobial activity. All the compounds were characterized by the spectral data and elemental anal. Thesynthesized compounds were initially screened for their antimicrobial activity against ATCC 6538, NCTC 10400, NCTC 10418 and ATCC 27853. During initial screening, compounds I [R = 2,4,6-trimethoxy; R1 = H, R = 2,4-dimethoxy; R1 = H, R = 4-bromo; R1 = H] presented significant antimicrobial activity through disk diffusion assay. These compounds were further evaluated for antimicrobial activity at different time points against Gram-pos. and Gram-neg. bacteria and presented significant activity for 6h. The activity was found to be greater against Gram-pos. bacteria. In contrast at 24h, the activity was found only against Gram-pos. bacteria except compound I [R = 4-bromo; R1 = H], showing activity against both types of bacteria. Compound I [R = 4-bromo; R1 = H] was found to have highest activity against both Gram-pos. and Gram-neg. bacteria. In the experiment, the researchers used many compounds, for example, 3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9Recommanded Product: 73387-46-9).

3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazole the presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. Recommanded Product: 73387-46-9

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics