Spectral and thermal studies on ruthenium carbonyl complexes with 5-trifluoromethyl-2,4-dihydropyrazol-3-one ligands was written by Soliman, Ahmed A.. And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2007.Computed Properties of C4H3F3N2O This article mentions the following:
Reactions of the cluster compound [Ru3(CO)12] with 5-trifluoromethyl-2,4-dihydropyrazol-3-one (HL1), 4-(2,4-dichlorophenylhydrazono)-5-trifluoromethyl-2,4-dihydropyrazol-3-one (H2L2), 4-(3-fluorophenylhydrazono)-5-trifluoromethyl-2,4-dihydropyrazol-3-one (H2L3), 4-(3-(trifluoromethyl)phenylhydrazono)-5-trifluoromethyl-2,4-dihydropyrazol-3-one (H2L4) and 4-(3-nitrophenylhydrazono)-5-trifluoromethyl-2,4-dihydropyrazol-3-one (H2L5) were carried out in benzene and under reduced pressure. The structures of the isolated complexes were elucidated using elemental analyses, IR, UV-visible, mass and NMR spectroscopy. All the complexes are diamagnetic and have trigonal bipyramidal structures [Ru(CO)4(HL1)] and [Ru(CO)3(H2L2-5)]. The thermal decompositions of the complexes were studied in correlation with the mass spectral fragmentation patterns. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)-1H-pyrazol-5(4H)-one (cas: 401-73-0Computed Properties of C4H3F3N2O).
3-(Trifluoromethyl)-1H-pyrazol-5(4H)-one (cas: 401-73-0) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Computed Properties of C4H3F3N2O
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics