An Efficient Synthesis of Isoxazoles and Pyrazoles under Ultrasound Irradiation was written by Huang, Zhi-Bin;Li, Li-Li;Zhao, Yan-Wei;Wang, Hui-Yuan;Shi, Da-Qing. And the article was included in Journal of Heterocyclic Chemistry in 2014.Formula: C9H7BrN2 This article mentions the following:
A series of 5-arylisoxazoles I (Ar = 4-ClC6H4, 4-CH3C6H4, 1-naphthyl, etc.; R= H, Me) and 5-aryl-1H-pyrazole derivatives II were synthesized by the reaction of 3-(dimethylamino)-1-arylprop-2-en-1-ones with hydroxylamine hydrochloride or hydrazine hydrate under ultrasound irradiation without using any catalyst. This method has the advantages of easier work-up, mild reaction condition, high yields, shorter reaction time, and environmentally benign procedure. In the experiment, the researchers used many compounds, for example, 3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9Formula: C9H7BrN2).
3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. The strategies for the synthesis of pyrazoles generally can be applied for the construction of indazoles. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Formula: C9H7BrN2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics