Synthesis and characterization of some symmetrical substituted 1-(2-chloroethyl)pyrazole-based chalcogenides was written by Pundir, S.;Mehta, S. K.;Mobin, S. M.;Bhasin, K. K.. And the article was included in Indian Journal of Heterocyclic Chemistry in 2017.Application In Synthesis of 4-Chloro-3,5-dimethyl-1H-pyrazole This article mentions the following:
The synthesis of some sym. substituted 1-(2-chloroethyl) pyrazole-based dichalcogenides I [X = H, Cl, Br, CHO; R = S, Se, Te] and monochalcogenides II [X = H, Cl] by reacting different 3,4,5-trisubstituted 1-(2-chloroethyl) pyrazole derivatives with in situ prepared Na2E2 (E = S, Se, Te) and sodium hydrogen selenide, resp. X-ray crystal structure determination of 1,2-bis (2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)ethyl)diselane I [X = Br; R = Se] revealed intermol. Se·N·H interactions between two mols. In the experiment, the researchers used many compounds, for example, 4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8Application In Synthesis of 4-Chloro-3,5-dimethyl-1H-pyrazole).
4-Chloro-3,5-dimethyl-1H-pyrazole (cas: 15953-73-8) belongs to pyrazole derivatives. As is the case with imidazoles, the pyrazole ring offers many opportunities to create new multiring systems that incorporate this heterocycle. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Application In Synthesis of 4-Chloro-3,5-dimethyl-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics