Sudheer Reddy, V.’s team published research in Russian Journal of Bioorganic Chemistry in 48 | CAS: 724710-02-5

Russian Journal of Bioorganic Chemistry published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C14H20BClO2, Product Details of C3H5BN2O2.

Sudheer Reddy, V. published the artcileSynthesis of Some New N-Substituted Imidazole Derivatives and Their In Vitro Antibacterial Investigation, Product Details of C3H5BN2O2, the publication is Russian Journal of Bioorganic Chemistry (2022), 48(3), 643-650, database is CAplus.

Here the synthesis of N-substituted imidazole derivatives I (X = 3-MeOC6H4, 4-O2NC6H4, 3,5-F2C6H3, etc.) based on Suzuki coupling reaction of I (X = Br) with various arylboronic acids using Pd(dppf)Cl2·CH2Cl2 as the catalyst and K2CO3 as a base in 1,4-dioxane/H2O (2 : 1) is described. The products were screened for their antibacterial activity against gram-pos. bacterial strains, Bacillus subtilis and Staphylococcus aureus, where the compounds I (X = 4-pyridinyl, 3-F-4-MeOC6H3, 3-NCC6H4, 3-FC6H4, 4-F-3-MeC6H3, 4-pyrazolyl) exhibited remarkable activity compared to the reference streptomycin.

Russian Journal of Bioorganic Chemistry published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C14H20BClO2, Product Details of C3H5BN2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics