Feid-Allah, Hassan M. published the artcileTrisubstituted pyrazoles of possible antidiabetic and antibacterial activity, Related Products of pyrazoles-derivatives, the publication is Pharmazie (1981), 36(11), 754-6, database is CAplus.
Condensation of benzalacetone and dibenzalacetone with 4-H2NSO2C6H4NHNH2 (I) and 2-pyridylhydrazine led to the corresponding hydrazones. These were readily cyclized to pyrazolines on heating with HCl. The reaction of substituted benzalacetophenones with I and 2-pyridylhydrazine gave the pyrazoline derivatives directly. Oxidation of the pyrazolines with Br-H2O afforded the pyrazoles. Reaction of epoxy-p-methoxybenzalacetophenone with I gave a hydroxapyrazoline which oxidized to the hydroxypyrazole with Br-H2O. Condensation of acylhydrazines with substituted benzalacetophenones afforded the corresponding acylhydrazones.
Pharmazie published new progress about 71203-35-5. 71203-35-5 belongs to pyrazoles-derivatives, auxiliary class GPCR/G Protein,Ras, name is 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, and the molecular formula is C22H21N3O3S, Related Products of pyrazoles-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics