Song, Zongqiang published the artcileSynthesis of 1,3-Dioxepine-Fused (Tricyclic) Bispyrazoles Involved with Pyrazolone Derivatives and Dichloromethane, Application of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Journal of Organic Chemistry (2022), 87(6), 4284-4290, database is CAplus and MEDLINE.
A simple and novel method was described for the synthesis of novel 1,3-dioxepine-fused (tricyclic) bispyrazoles I (R = H, Me, t-Bu, Cl, etc.; R1 = H; RR1 = -CH=CH-CH=CH-; R2 = Me, CF3, i-Pr, Ph; R3 = H, Me). It involves a Cs2CO3 mediated O-alkylation of readily available pyrazolone derivatives II with dichloromethane as methylene source followed by PhI(OAc)2-mediated intramol. oxidative biheteroaryl coupling under mild conditions. This scalable protocol was applied for the preparation of valuable and novel 1,3-dioxepine-fused (tricyclic) bispyrazoles I which could find potential applications in medicinal or material chem.
Journal of Organic Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H19NO3, Application of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.
Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics