Faid-Allah, Hassan M.’s team published research in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 27B | CAS: 71203-35-5

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 71203-35-5. 71203-35-5 belongs to pyrazoles-derivatives, auxiliary class GPCR/G Protein,Ras, name is 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, and the molecular formula is C22H21N3O3S, Synthetic Route of 71203-35-5.

Faid-Allah, Hassan M. published the artcilePyrazole derivatives with possible hypoglycemic activity, Synthetic Route of 71203-35-5, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1988), 27B(3), 245-9, database is CAplus.

Condensation reaction of p-H2NSO2C6H4NHNH2.HCl with p-RC6H4CH:CHCOC6H4R1–p (R = H, R1 = OMe, Cl, Br, NH2; R = MeO, R1 = H) gave the corresponding hydrazones in the presence of NaOAc; in the absence of NaOAc, the products were pyrazolines I (R2 = H). Oxidation of I with Br gave pyrazoles II (R2 = H). Acylation and thioacylation of I and II with R3NCX (R3 = Pr, Bu, Ph, cyclohexyl, X = O; R3 = allyl, Ph, cyclohexyl, PhCH2, X = S) gave ureas and thioureas I and II [R2 = CXNHR3]. Cyclocondensation of II (R2 = CSNHR3) with Br(CH2)nCO2Et (n = 1,2) gave imino heterocycles III.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 71203-35-5. 71203-35-5 belongs to pyrazoles-derivatives, auxiliary class GPCR/G Protein,Ras, name is 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, and the molecular formula is C22H21N3O3S, Synthetic Route of 71203-35-5.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics