Parekh, Nikhil M.’s team published research in Medicinal Chemistry Research in 21 | CAS: 14580-22-4

Medicinal Chemistry Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Product Details of C10H9ClN2O.

Parekh, Nikhil M. published the artcileAntituberculosis and antibacterial evaluations of some novel phenyl pyrazolone-substituted 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives, Product Details of C10H9ClN2O, the publication is Medicinal Chemistry Research (2012), 21(12), 4168-4176, database is CAplus.

Coupling of various phenylpyrazolone derivatives with diazonium salt of 1H-benzo[g]pyrazolo[3,4-b]quinolin-3-ylamine gave a series of heterocyclic azo compounds All the synthesized azo compounds have been characterized by their percentage yield, elemental, and spectral analyses. These new compounds were evaluated for their in vitro antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. Furthermore, the synthesized compounds were tested for in vitro antituberculosis activity against Mycobacterium tuberculosis. Streptomycin, Isoniazid, Rifampicin, and Ethambutol were used as standards in this investigation.

Medicinal Chemistry Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Product Details of C10H9ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics