Brzozowski, Zdzislaw’s team published research in Acta Poloniae Pharmaceutica in 38 | CAS: 53355-55-8

Acta Poloniae Pharmaceutica published new progress about 53355-55-8. 53355-55-8 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Chloride,acyl chloride,Amide, name is 1H-Pyrazole-1-carbonyl chloride, and the molecular formula is C4H3ClN2O, Name: 1H-Pyrazole-1-carbonyl chloride.

Brzozowski, Zdzislaw published the artcileDerivatives of 1-pyrazole carboxylic acid. I. Synthesis of certain 1-pyrazolecarbonyl chlorides, Name: 1H-Pyrazole-1-carbonyl chloride, the publication is Acta Poloniae Pharmaceutica (1981), 38(4), 393-8, database is CAplus.

Fifteen acid chlorides I (R = H, Me, Et; R1 = H, Me, Et, Pr, Bu, PhCH2 Cl; R2 = H and Me) were prepared in 87-98% yield from the corresponding 1H– pyrazoles and COCl2 in PhMe. Three I were converted into the corresponding amides by reaction with NH3(g) in Et2O. The mass spectral fragmentation of 3-ethyl-4-methyl-1-pyrazole carboxamide is presented.

Acta Poloniae Pharmaceutica published new progress about 53355-55-8. 53355-55-8 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Chloride,acyl chloride,Amide, name is 1H-Pyrazole-1-carbonyl chloride, and the molecular formula is C4H3ClN2O, Name: 1H-Pyrazole-1-carbonyl chloride.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics