Lee, Jongkook’s team published research in Bioorganic & Medicinal Chemistry Letters in 22 | CAS: 724710-02-5

Bioorganic & Medicinal Chemistry Letters published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C3H5BN2O2, Related Products of pyrazoles-derivatives.

Lee, Jongkook published the artcileSynthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors, Related Products of pyrazoles-derivatives, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(12), 4044-4048, database is CAplus and MEDLINE.

A series of hydroxybenzoxazole derivatives, e.g., I [R2 = H, Cl, MeNH, MeCONH, R3 = H, MeCO, Me(OH)CH, 3-pyrazolyl, etc., R4 = H, 2-pyridinyl, 4-MeOC6H4, Me2CHNH], was synthesized, and their c-Met kinase inhibitory activity was evaluated. Described herein is a potent c-Met inhibitor by structural modification of the parent benzoxazole scaffold, with particular focus on the hydroxyl substituent of the benzoxazole moiety.

Bioorganic & Medicinal Chemistry Letters published new progress about 724710-02-5. 724710-02-5 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Boronic acid and ester,Pyrazole,Boronic Acids,Boronic acid and ester, name is (1H-Pyrazol-5-yl)boronic acid, and the molecular formula is C3H5BN2O2, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics