Synthesis of N-Methoxy-N-methyl-β-enaminoketoesters: New synthetic precursors for the regioselective synthesis of heterocyclic compounds. [Erratum to document cited in CA145:271693] was written by Persson, Tobias;Nielsen, John. And the article was included in Organic Letters in 2007.Recommanded Product: Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate The following contents are mentioned in the article:
In the Supporting Information section, on page S6, “1 M aq HC1 (5 mL)” should read “1 M aq HC1 (2 mL)”. A corrected Supporting Information file has been posted online. This study involved multiple reactions and reactants, such as Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8Recommanded Product: Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate).
Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8) belongs to pyrazole derivatives. Pyrazole is a weak base, with pKb 11.5 (pKa of the conjugated acid 2.49 at 25 °C).Pyrazole used as a ligand to prepare organometallic compounds. The pyrazole ring is resistant to oxidation and reduction but the groups, such as alkyl and formyl attached to the ring, are oxidized to respective acids. Only electrolytic oxidation, ozonolysis, and a strong base cause ring opening.Recommanded Product: Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics