Dalla Croce, Piero et al. published their research in Annali di Chimica (Rome, Italy) in 1973 | CAS: 17355-75-8

Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Formula: C18H16N2O2

Reaction of hydrazonic halides and stabilized phosphorus ylides. Evidence for a two step mechanism was written by Dalla Croce, Piero. And the article was included in Annali di Chimica (Rome, Italy) in 1973.Formula: C18H16N2O2 The following contents are mentioned in the article:

The reaction of RCCl:NNHR1 (R = CO2Et, Ac, R1 = Ph, p-O2NC6H4, o-O2NC6H4) with Ph3P:CHCOR2 (R2 = Ph, Me, CO2Et, NMe2, OEt) gave the corresponding I in a 2 step reaction via R2COCH(P+Ph3)CR:NN-R1. R2COC(:PPh3)CR:NNHR1 was isolated in the reaction. This study involved multiple reactions and reactants, such as Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8Formula: C18H16N2O2).

Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8) belongs to pyrazole derivatives. An alternative way to synthesize multisubstituted pyrazoles is the Csingle bondH arylation of simple pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Formula: C18H16N2O2

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics