Allin, Steven M. published the artcileBu3SnH-Mediated radical cyclization onto azoles, Safety of 4-Bromo-1-tosyl-1H-pyrazole, the main research area is bicyclic pyrrole imidazole pyrazole preparation.
Alkyl radicals have been cyclized onto pyrroles, imidazoles and pyrazoles, and acyl radicals cyclized onto pyrroles, using Bu3SnH-, (Me3Si)3SiH- and Bu3GeH-mediated aromatic homolytic substitution for the synthesis of bicyclic N-heterocycles. The reactions yield intermediate π-radicals that lose hydrogen in the rearomatization step of the aromatic homolytic substitution. Mechanistic studies of these rearomatization steps indicate aromatic homolytic substitution in which the initiator or breakdown products from the inhibitor are responsible for the H-abstraction step.
Tetrahedron published new progress about Crystal structure. 116228-41-2 belongs to class pyrazoles-derivatives, name is 4-Bromo-1-tosyl-1H-pyrazole, and the molecular formula is C10H9BrN2O2S, Safety of 4-Bromo-1-tosyl-1H-pyrazole.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics