Zheng, Zhaoyan published the artcileTautomerism-Dependent Ring Construction of N-Heterocyclic Compounds from the Reactions of 1-Alkynyl Fischer Carbene Complexes and Substituted Pyrazolinones, Safety of 5-Phenyl-1H-pyrazol-3(2H)-one, the main research area is pyrazolone fused preparation alkynyl Fischer carbene complex.
Four types of N-heterocyclic ring systems were successfully constructed from the reactions of 1-alkynyl Fischer carbene complexes (OC)5M:C(OEt)CCPh (I, M = Cr, W) and substituted pyrazolinones. Reactions of I with 3-methyl-, 3-propyl-, 3,4-dimethyl-, 3,4-trimethylene-, or 3,4-tetramethylene-2-pyrazolin-5-one generated three kinds of Fischer aminocarbene complexes, and reactions of I with 3-phenyl-2-pyrazolin-5-one and its tautomer 3-phenyl-3-pyrazolin-5-one, gave Fischer alkoxycarbene complexes as the major products and aminocarbene complexes as the minor products. Multiple tautomerism of pyrazolinones is attributed to the versatile formation of N-heterocyclic Fischer carbene complexes. Oxidative demetalation of the complexes with pyridine N-oxide or m-chloroperoxybenzoic acid efficiently afforded organic carbonyl products, and thus, strongly fluorescent syn-mixed-bimanes were prepared The present findings constitute an alternative new method to synthesize mixed bimanes and other novel N-heterocyclic compounds
Journal of Organic Chemistry published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 27412-71-1 belongs to class pyrazoles-derivatives, name is 5-Phenyl-1H-pyrazol-3(2H)-one, and the molecular formula is C9H8N2O, Safety of 5-Phenyl-1H-pyrazol-3(2H)-one.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics