Salvado, Oriol published the artcileStereoselective Cyclopropanation of 1,1-Diborylalkenes via Palladium-Catalyzed (Trimethylsilyl)diazomethane Insertion, Synthetic Route of 111562-32-4, the main research area is diborylalkene preparation silyl cyclopropanation insertion reaction diazomethane; chiral silyl boryl naphthyl cyclopropane preparation crystal structure; mol structure chiral silyl boryl naphthyl cyclopropane; diborylation aldehyde; diborylcyclopropane stereoselective preparation.
Pd catalyzes the cyclopropanation of 2-substituted 1,1-diborylalkenes with (trimethylsilyl)diazomethane. The relative stereoselectivity is controlled via a carbene insertion sequence generating an exclusive anti conformation between the R and SiMe3 substituents. Mixed 1,1-diborylalkenes also contributed to the formation of stereoselective B, B, Si-cyclopropanes. Orthogonal activation with NaOtBu gives protodeborylation preferentially on the B moiety syn to the aryl group. Further oxidation gives access to polyfunctional cyclopropyl alcs. with controlled enantioselectivity when chiral boryl motifs are involved.
Organic Letters published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 111562-32-4 belongs to class pyrazoles-derivatives, name is 2-(1H-Pyrazol-3-yl)aniline, and the molecular formula is C9H9N3, Synthetic Route of 111562-32-4.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics