Pal, Sarbani published the artcileHigh speed synthesis of pyrazolones using microwave-assisted neat reaction technology, Related Products of pyrazoles-derivatives, the main research area is keto ester cyclization hydrazine microwave; pyrazolone preparation reaction acrylate; spiro cyclohexane pyrazolone preparation.
A high speed, solvent-free, and practical synthesis of pyrazolones under microwave irradiation was described. This greener synthetic methodol. involves the reaction of β-keto ester with substituted or unsubstituted hydrazine and provides a simple and straightforward one-pot approach for the synthesis of a variety of pyrazolone derivatives with high regioselectivity. These pyrazolones can exist in different tautomeric forms in solution and the aryl ring of 2-aryl pyrazol-3-ones remain twisted with respect to the pyrazole plane in the crystal state. Mechanism of the reaction accounting the regioselectivity was proposed. One of the pyrazolones obtained via this process was utilized to prepare a spiro-cyclohexanone derivative of potential biol. significance.
Journal of the Brazilian Chemical Society published new progress about Hydrazines Role: RCT (Reactant), RACT (Reactant or Reagent). 27412-71-1 belongs to class pyrazoles-derivatives, name is 5-Phenyl-1H-pyrazol-3(2H)-one, and the molecular formula is C9H8N2O, Related Products of pyrazoles-derivatives.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics